Custom assays
Precision solutions for your skin challenges
Our research partnering services are specifically tailored to address your research questions, providing significant value to our clients. The results that can be derived from the application of TenSkin™ are impressive because of the integrity of the skin’s physiology that is maintained by the re-introduction of tension to the skin tissue. The restoration of the skin’s mechanical homeostasis is also important for many complex physiological functions.
Building on our initial offering, the TenSkin™ TS-18, which offers 2.5 cm2 (18 mm diameter) of viable full-thickness human skin, our range now includes:
- The TS-25 and TS-40 large area models, offering 4.9 cm2 and 12.5 cm2 areas of useable skin, respectively. These variants emerged from interesting and productive collaborations in the fields of aesthetic medical device development (e.g., micro-needling), and novel drug delivery system evaluations (e.g., microneedle array patches, and novel injectors).
- The TSW-18 wounded model, available in two sub-variants, either wounded by precision fractional laser ablation or shallow biopsy incision, has been used across a wide variety of fields ranging from the evaluation of OTC treatments to military applications involving decontamination of simulated battlefield wounds in the presence of chemical agents.
- The TSA-18 adipose model, which retains an 8 mm thick layer of hypodermis, was initially developed for applications in aesthetic dermatology for the evaluation of hyaluronic acid fillers delivered through subcutaneous injection. Applications in other areas of injection delivery, e.g., therapeutic and vaccine, are also possible.
Case study -Ten Bio Climate Chamber
Using our proprietary climate chamber, we can expose the skin surface in our TenSkin™ model to defined environmental conditions while isolating the culture media and dermal side of the tissue, retaining standard culture conditions (e.g., temperature, pH). Our clients therefore benefit from our offer of testing under defined climate parameters, enabling the evaluation of not only product performance in different climates but how those products can protect the skin in more extreme environments.