Ten Bio News

Topical drug delivery has evolved from simple creams to increasingly sophisticated systems designed to transport therapeutic molecules through the skin. While many small molecules can penetrate the skin barrier, larger and more complex therapeutics present new challenges. In this article, we explore how topical and transdermal delivery is evolving and why human-relevant skin models are becoming increasingly important for understanding how new therapies interact with the skin.

Microneedle technologies are advancing rapidly, but accurately assessing their performance depends on how closely test systems reflect real human skin. Preserving physiological tension is a key factor in generating reliable, human-relevant data.

Wearable technologies are evolving into platforms that generate continuous insight into skin health and underlying physiology. As devices become more biologically integrated, skin is emerging as a critical interface — shaping what wearables can measure and how reliably they perform. This article explores where skin-interfacing wearables are heading and how TenSkin™ helps bridge early development and real-world use.

Eczema (atopic dermatitis) affects millions worldwide, yet many of its underlying mechanisms are still being uncovered. In this article, Professor Alan Irvine outlines what science understands about the condition’s causes — from the role of the skin barrier and immune pathways to the influence of the microbiome and environment — and explains how these insights are shaping innovative approaches to prevention and treatment.

Mouse models remain a cornerstone of dermatology research, but their differences from human skin — in follicle density, barrier function, and wound healing — can limit translation. This article explores the critical factors that shape absorption and pharmacological activity, and considers how human-based models can improve predictive power.

Explore how TenSkin™, Ten Bio’s ex vivo human skin model, is helping researchers study psoriasis with greater accuracy and human relevance — reducing reliance on animal testing and improving translational outcomes.

This spring, Ten Bio joined leading voices in dermatology at events in France, the US, and Australia—spotlighting TenSkin™ as a powerful, human-relevant alternative to animal testing. From photoprotection to microneedle delivery, the message was clear: innovation needs better models.

Ten Bio has officially joined the James Hutton Institute’s Dundee campus, marking a new chapter in its mission to advance human-relevant dermatology research. The move supports Ten Bio’s continued growth and fosters collaboration with one of Scotland’s leading scientific communities.

As regulatory momentum builds and new human-relevant technologies emerge, the conversation is shifting. The question is no longer if we can replace animal testing in skin research — but how fast. This article explores why models like TenSkin™ offer a scalable, scientifically robust alternative that’s already reshaping preclinical research.