Ten Bio News

Protective effects of antioxidant mix pre-treatment against visible light-induced damage in dark skin phototype
Visible light (VL) accounts for approximately 50% of the solar radiation reaching Earth’s surface and has emerged as a major contributor to skin photoaging and

Beyond clinical testing: Why molecular evidence is becoming essential for cosmetic claims
Clinical studies show whether consumers experience measurable product benefits, but they often cannot explain why. In this article, we explore how molecular evidence from ex vivo human skin models are strengthening cosmetic claim substantiation by connecting visible outcomes with the biological mechanisms that drive them.

Can AI improve predictive skin research?
Artificial intelligence is transforming skin research by uncovering biological patterns and predicting tissue responses from increasingly large and complex datasets. But AI is only as reliable as the biological data used to train and validate it. Discover why physiologically relevant human skin models remain essential for translating AI predictions into meaningful biological insight.

Longevity beauty in 2026: From anti-aging claims to biological evidence
Longevity beauty is reshaping the dermo-cosmetics sector, shifting the focus from traditional anti-aging claims toward biologically relevant evidence. As innovations such as peptides, exosomes and microbiome-focused technologies gain momentum, the challenge is no longer simply developing new actives, but demonstrating their impact on skin biology through predictive, human-relevant testing approaches.

From creams to complex molecules: The evolving science of topical delivery
Topical drug delivery has evolved from simple creams to increasingly sophisticated systems designed to transport therapeutic molecules through the skin. While many small molecules can penetrate the skin barrier, larger and more complex therapeutics present new challenges. In this article, we explore how topical and transdermal delivery is evolving and why human-relevant skin models are becoming increasingly important for understanding how new therapies interact with the skin.

Microneedle testing: why skin tension matters for human-relevant data
Microneedle technologies are advancing rapidly, but accurately assessing their performance depends on how closely test systems reflect real human skin. Preserving physiological tension is a key factor in generating reliable, human-relevant data.

The future of wearable technologies in skin research
Wearable technologies are evolving into platforms that generate continuous insight into skin health and underlying physiology. As devices become more biologically integrated, skin is emerging as a critical interface — shaping what wearables can measure and how reliably they perform. This article explores where skin-interfacing wearables are heading and how TenSkin™ helps bridge early development and real-world use.

Understanding eczema: Beyond symptoms
Eczema (atopic dermatitis) affects millions worldwide, yet many of its underlying mechanisms are still being uncovered. In this article, Professor Alan Irvine outlines what science understands about the condition’s causes — from the role of the skin barrier and immune pathways to the influence of the microbiome and environment — and explains how these insights are shaping innovative approaches to prevention and treatment.

Bridging the gap: Comparing topical drug absorption and activity in mouse and human skin models
Mouse models remain a cornerstone of dermatology research, but their differences from human skin — in follicle density, barrier function, and wound healing — can limit translation. This article explores the critical factors that shape absorption and pharmacological activity, and considers how human-based models can improve predictive power.

Why psoriasis research needs a human-relevant approach — and how ex vivo models can deliver
Explore how TenSkin™, Ten Bio’s ex vivo human skin model, is helping researchers study psoriasis with greater accuracy and human relevance — reducing reliance on animal testing and improving translational outcomes.

Predicting human response to gene-based therapies in preclinical evaluation
Why do so many gene therapies fail in clinical trials? A closer look at the preclinical gap—and how TenSkin™ is helping close it.

Beyond animal models: The future of skin testing is human-relevant and ready
As regulatory momentum builds and new human-relevant technologies emerge, the conversation is shifting. The question is no longer if we can replace animal testing in skin research — but how fast. This article explores why models like TenSkin™ offer a scalable, scientifically robust alternative that’s already reshaping preclinical research.

Setting the standard: How TenSkin is shaping regulatory change in skin testing
As regulators move away from animal testing, clear validation frameworks are needed to support alternatives. Explant models like TenSkin™ offer a human-relevant solution for preclinical skin research, improving predictability and reproducibility.

Pollution protection
Urban pollution drives demand for advanced skincare. Ten Bio’s TenSkin™ offers a next generation ex vivo model to test anti-pollution products, providing crucial insights that accelerate the development of scientifically validated, high-impact solutions.

Happy Holidays 2024
Spreading Holiday cheer – from the Ten Bio team to all of our clients, collaborators and partners – past, present and future! As the year winds down, we want to take a moment to express a heartfelt thank you for being a part of our journey through 2024.

The advantages of extended viability in TenSkin™ for dermatological research
Ten Bio’s TenSkin™ ex vivo human skin model offers two-week viability, enhancing the depth and reliability of skin studies, allowing for more detailed insights into skin health and treatment efficacy.