Ten Bio News

Protective effects of antioxidant mix pre-treatment against visible light-induced damage in dark skin phototype
Visible light (VL) accounts for approximately 50% of the solar radiation reaching Earth’s surface and has emerged as a major contributor to skin photoaging and

Beyond clinical testing: Why molecular evidence is becoming essential for cosmetic claims
Clinical studies show whether consumers experience measurable product benefits, but they often cannot explain why. In this article, we explore how molecular evidence from ex vivo human skin models are strengthening cosmetic claim substantiation by connecting visible outcomes with the biological mechanisms that drive them.

Can AI improve predictive skin research?
Artificial intelligence is transforming skin research by uncovering biological patterns and predicting tissue responses from increasingly large and complex datasets. But AI is only as reliable as the biological data used to train and validate it. Discover why physiologically relevant human skin models remain essential for translating AI predictions into meaningful biological insight.

Longevity beauty in 2026: From anti-aging claims to biological evidence
Longevity beauty is reshaping the dermo-cosmetics sector, shifting the focus from traditional anti-aging claims toward biologically relevant evidence. As innovations such as peptides, exosomes and microbiome-focused technologies gain momentum, the challenge is no longer simply developing new actives, but demonstrating their impact on skin biology through predictive, human-relevant testing approaches.

From creams to complex molecules: The evolving science of topical delivery
Topical drug delivery has evolved from simple creams to increasingly sophisticated systems designed to transport therapeutic molecules through the skin. While many small molecules can penetrate the skin barrier, larger and more complex therapeutics present new challenges. In this article, we explore how topical and transdermal delivery is evolving and why human-relevant skin models are becoming increasingly important for understanding how new therapies interact with the skin.

Microneedle testing: why skin tension matters for human-relevant data
Microneedle technologies are advancing rapidly, but accurately assessing their performance depends on how closely test systems reflect real human skin. Preserving physiological tension is a key factor in generating reliable, human-relevant data.

The future of wearable technologies in skin research
Wearable technologies are evolving into platforms that generate continuous insight into skin health and underlying physiology. As devices become more biologically integrated, skin is emerging as a critical interface — shaping what wearables can measure and how reliably they perform. This article explores where skin-interfacing wearables are heading and how TenSkin™ helps bridge early development and real-world use.

Understanding eczema: Beyond symptoms
Eczema (atopic dermatitis) affects millions worldwide, yet many of its underlying mechanisms are still being uncovered. In this article, Professor Alan Irvine outlines what science understands about the condition’s causes — from the role of the skin barrier and immune pathways to the influence of the microbiome and environment — and explains how these insights are shaping innovative approaches to prevention and treatment.

Bridging the gap: Comparing topical drug absorption and activity in mouse and human skin models
Mouse models remain a cornerstone of dermatology research, but their differences from human skin — in follicle density, barrier function, and wound healing — can limit translation. This article explores the critical factors that shape absorption and pharmacological activity, and considers how human-based models can improve predictive power.

Why psoriasis research needs a human-relevant approach — and how ex vivo models can deliver
Explore how TenSkin™, Ten Bio’s ex vivo human skin model, is helping researchers study psoriasis with greater accuracy and human relevance — reducing reliance on animal testing and improving translational outcomes.

Bring me sunshine!
Exploring the effects of sun exposure using explant skin. Enjoyment of sunshine is a quintessential aspect of the human experience. Exposure provides a myriad of

Tension as a key factor in skin responses to pollution
This study explores how physiological tension affects skin responses to ozone pollution using the TenSkin™ model. Findings reveal tension modulates the expression of antimicrobial peptides and markers of oxidative stress and inflammation, highlighting its importance in skin health studies.

Advances and Opportunities in (Pre)Clinical Testing for Cosmetics and Personal Care
We are pleased to share this Global Perspectives Column in EURO COSMETICS Mag written by Deanna Utroske. Ten Bio emphasises scientific discipline and rigour in all of our

Scientific Conferences R Ten Bio
Since Ten Bio launched in the autumn of 2020 our attendance at conferences, symposia etc. has been the central plank to our market engagement strategy.

TenSkin™– its role in reducing animal testing in skin research.
TenSkinᵀᴹ – its role in reducing animal testing in skin research. Generate more predictive preclinical data without animal testing.

Mechanical tension influences the immunocompetency of ex vivo skin tissue
Human-relevant testing methods using donated skin tissue offer a promising alternative to animal models. Our ex vivo culture system restores physiological tension in skin, preserving structure, function, and immune cells like Langerhans cells, enabling immune activation studies for up to seven days.