Ten Bio News

Protective effects of antioxidant mix pre-treatment against visible light-induced damage in dark skin phototype
Visible light (VL) accounts for approximately 50% of the solar radiation reaching Earth’s surface and has emerged as a major contributor to skin photoaging and

Beyond clinical testing: Why molecular evidence is becoming essential for cosmetic claims
Clinical studies show whether consumers experience measurable product benefits, but they often cannot explain why. In this article, we explore how molecular evidence from ex vivo human skin models are strengthening cosmetic claim substantiation by connecting visible outcomes with the biological mechanisms that drive them.

Can AI improve predictive skin research?
Artificial intelligence is transforming skin research by uncovering biological patterns and predicting tissue responses from increasingly large and complex datasets. But AI is only as reliable as the biological data used to train and validate it. Discover why physiologically relevant human skin models remain essential for translating AI predictions into meaningful biological insight.

Longevity beauty in 2026: From anti-aging claims to biological evidence
Longevity beauty is reshaping the dermo-cosmetics sector, shifting the focus from traditional anti-aging claims toward biologically relevant evidence. As innovations such as peptides, exosomes and microbiome-focused technologies gain momentum, the challenge is no longer simply developing new actives, but demonstrating their impact on skin biology through predictive, human-relevant testing approaches.

From creams to complex molecules: The evolving science of topical delivery
Topical drug delivery has evolved from simple creams to increasingly sophisticated systems designed to transport therapeutic molecules through the skin. While many small molecules can penetrate the skin barrier, larger and more complex therapeutics present new challenges. In this article, we explore how topical and transdermal delivery is evolving and why human-relevant skin models are becoming increasingly important for understanding how new therapies interact with the skin.

Microneedle testing: why skin tension matters for human-relevant data
Microneedle technologies are advancing rapidly, but accurately assessing their performance depends on how closely test systems reflect real human skin. Preserving physiological tension is a key factor in generating reliable, human-relevant data.

The future of wearable technologies in skin research
Wearable technologies are evolving into platforms that generate continuous insight into skin health and underlying physiology. As devices become more biologically integrated, skin is emerging as a critical interface — shaping what wearables can measure and how reliably they perform. This article explores where skin-interfacing wearables are heading and how TenSkin™ helps bridge early development and real-world use.

Understanding eczema: Beyond symptoms
Eczema (atopic dermatitis) affects millions worldwide, yet many of its underlying mechanisms are still being uncovered. In this article, Professor Alan Irvine outlines what science understands about the condition’s causes — from the role of the skin barrier and immune pathways to the influence of the microbiome and environment — and explains how these insights are shaping innovative approaches to prevention and treatment.

Bridging the gap: Comparing topical drug absorption and activity in mouse and human skin models
Mouse models remain a cornerstone of dermatology research, but their differences from human skin — in follicle density, barrier function, and wound healing — can limit translation. This article explores the critical factors that shape absorption and pharmacological activity, and considers how human-based models can improve predictive power.

Why psoriasis research needs a human-relevant approach — and how ex vivo models can deliver
Explore how TenSkin™, Ten Bio’s ex vivo human skin model, is helping researchers study psoriasis with greater accuracy and human relevance — reducing reliance on animal testing and improving translational outcomes.

A tensioned human skin explant model used for preliminary assessment of chemexfoliant-stimulated bioeffects
Our latest study, using the TenSkinᵀᴹ model, demonstrates how our ex vivo platform is delivering biologically relevant insights into the effects of chemexfoliation (chemical peel) treatments on human skin.

Ten Bio shortlisted for The Courier Business Awards
We are proud to be announced as finalist in The Courier Business Awards in the Innovation and Technology category.

The importance of using a diverse range of skin in aesthetic dermatology testing
The Ten Bio team explore why incorporating all Fitzpatrick types in aesthetic dermatology testing is not just a best practice – it is a scientific imperative.

Preliminary assessment of microneedle wound healing in a full-thickness ex vivo human skin model cultured at physiological tension
This study evaluated skin recovery using the TenSkin™ model after microneedle application (dissolvable and non-dissolving types). Histological and immunofluorescence analyses tracked wound healing, comparing results with laser ablation.

The effect of mechanical tension on bolus morphology and integration following intradermal injection in an ex vivo human skin model
Intradermal injection studies benefit from ex vivo human skin models, but traditional relaxed-state models lack physiological tension, impacting tissue integrity and fiber alignment. The TenSkin™ model addresses this, offering more accurate dermal responses and improved integration of hyaluronic acid-based fillers.

Ten Bio’s agile innovation in climate-smart skincare
At Ten Bio, we continually innovate to meet our client’s needs, helping them to overcome their R&D challenges and position themselves at the leading edge of their respective markets. Read about our agile innovation in climate-smart skincare in our latest article…