Ten Bio News
Bring me sunshine!
Exploring the effects of sun exposure using explant skin. Enjoyment of sunshine is a quintessential aspect of the human experience. Exposure provides a myriad of
Tension as a key factor in skin responses to pollution
This study explores how physiological tension affects skin responses to ozone pollution using the TenSkin™ model. Findings reveal tension modulates the expression of antimicrobial peptides and markers of oxidative stress and inflammation, highlighting its importance in skin health studies.
Advances and Opportunities in (Pre)Clinical Testing for Cosmetics and Personal Care
We are pleased to share this Global Perspectives Column in EURO COSMETICS Mag written by Deanna Utroske. Ten Bio emphasises scientific discipline and rigour in all of our
Scientific Conferences R Ten Bio
Since Ten Bio launched in the autumn of 2020 our attendance at conferences, symposia etc. has been the central plank to our market engagement strategy.
TenSkin™– its role in reducing animal testing in skin research.
TenSkinᵀᴹ – its role in reducing animal testing in skin research. Generate more predictive preclinical data without animal testing.
Mechanical tension influences the immunocompetency of ex vivo skin tissue
Human-relevant testing methods using donated skin tissue offer a promising alternative to animal models. Our ex vivo culture system restores physiological tension in skin, preserving structure, function, and immune cells like Langerhans cells, enabling immune activation studies for up to seven days.
TenSkin™ – The perfect platform for microneedle applications.
Dr Paul Campbell gives his perspective on potential research avenues with TenSkin™. ‘Having worked directly with the company whilst on secondment over the past year,
Ten Bio is in Japan!
Ten Bio 社は日本にあります. In May this year, Ten Bio will attend the global session of the International Societies for Investigative Dermatology (ISID) to be held
TenSkin™ – the number one choice for skin research
Professor Giuseppe Valacchi has a global reputation for his work in expanding the understanding of cellular and molecular mechanisms that define the physio-pathological responses of skin tissue. In this interview, Professor Valacchi describes why TenSkinTM is his first choice for skin research and why he is pleased to lead Ten Bio’s Scientific Advisory Board . .
Comparative wound healing in cultured tissues vs ex-vivo tissues
This study compared a 3D cultured skin model with Ten Bio’s tensioned ex vivo TenSkin model for battlefield wound simulation. Results showed TenSkin more closely replicates healing seen in trauma patients, making it a superior platform for injury research.
Predicting human response to gene-based therapies in preclinical evaluation
Why do so many gene therapies fail in clinical trials? A closer look at the preclinical gap—and how TenSkin™ is helping close it.
Beyond animal models: The future of skin testing is human-relevant and ready
As regulatory momentum builds and new human-relevant technologies emerge, the conversation is shifting. The question is no longer if we can replace animal testing in skin research — but how fast. This article explores why models like TenSkin™ offer a scalable, scientifically robust alternative that’s already reshaping preclinical research.
Setting the standard: How TenSkin is shaping regulatory change in skin testing
As regulators move away from animal testing, clear validation frameworks are needed to support alternatives. Explant models like TenSkin™ offer a human-relevant solution for preclinical skin research, improving predictability and reproducibility.
Pollution protection
Urban pollution drives demand for advanced skincare. Ten Bio’s TenSkin™ offers a next generation ex vivo model to test anti-pollution products, providing crucial insights that accelerate the development of scientifically validated, high-impact solutions.
Happy Holidays 2024
Spreading Holiday cheer – from the Ten Bio team to all of our clients, collaborators and partners – past, present and future! As the year winds down, we want to take a moment to express a heartfelt thank you for being a part of our journey through 2024.
The advantages of extended viability in TenSkin™ for dermatological research
Ten Bio’s TenSkin™ ex vivo human skin model offers two-week viability, enhancing the depth and reliability of skin studies, allowing for more detailed insights into skin health and treatment efficacy.