Ten Bio News
The importance of using a diverse range of skin in aesthetic dermatology testing
The Ten Bio team explore why incorporating all Fitzpatrick types in aesthetic dermatology testing is not just a best practice – it is a scientific imperative.
Preliminary assessment of microneedle wound healing in a full-thickness ex vivo human skin model cultured at physiological tension
This study evaluated skin recovery using the TenSkin™ model after microneedle application (dissolvable and non-dissolving types). Histological and immunofluorescence analyses tracked wound healing, comparing results with laser ablation.
The effect of mechanical tension on bolus morphology and integration following intradermal injection in an ex vivo human skin model
Intradermal injection studies benefit from ex vivo human skin models, but traditional relaxed-state models lack physiological tension, impacting tissue integrity and fiber alignment. The TenSkin™ model addresses this, offering more accurate dermal responses and improved integration of hyaluronic acid-based fillers.
Ten Bio’s agile innovation in climate-smart skincare
At Ten Bio, we continually innovate to meet our client’s needs, helping them to overcome their R&D challenges and position themselves at the leading edge of their respective markets. Read about our agile innovation in climate-smart skincare in our latest article…
The Sun Factor
Our patented TenSkin™ model can be used to evaluate the efficacy and tolerability of sunscreens, while also exploring the underlying biological processes that arise following exposure to the sun. In this article, the scientific team at Ten Bio explore the effects of sun exposure and the role of explant skin in the evaluation of sunscreen products and the investigation of the effects of over-exposure.
Ten Bio conferencing in 2024
Ken Fyvie shares plans for the 2024 conference season, read more to find out which events we will be attending.
Tissue integration of hyaluronic acid -containing dermal fillers: an optimized approach using tensioned ex-vivo human skin
Using the TenSkin™ ex-vivo model, this study highlights the importance of mechanical tension in assessing dermal filler integration. TenSkin™ provides a reliable platform for evaluating filler performance and guiding product development.
Precision solutions for your skin research challenges
At Ten Bio we enhance pre-clinical skin testing for our clients through the provision of our unique portfolio of explant skin platform TenSkin™. Our range includes large area models for novel drug delivery system evaluations, the adipose model for applications in subcutaneous injection delivery, and a wounded model for use in treatment & healing evaluations.
As we stride into 2024…
A very Happy and Prosperous New Year to all of Ten Bio’s clients current and future, suppliers, investors, and staff. We are all excited at the prospects of our business in 2024.
Happy Holidays 2023!
The Ten Bio team wishes you Happy Holidays and a Prosperous New Year! As our successful year comes to a close, we would like to thank our clients and business partners for their continued confidence, trust and engagement. We look forward to strengthening our collaborations in 2024 and are excited by the prospect of new partnerships and by the new science that will emerge in the coming year.
The future of wearable technologies in skin research
Wearable technologies are evolving into platforms that generate continuous insight into skin health and underlying physiology. As devices become more biologically integrated, skin is emerging as a critical interface — shaping what wearables can measure and how reliably they perform. This article explores where skin-interfacing wearables are heading and how TenSkin™ helps bridge early development and real-world use.
Understanding eczema: Beyond symptoms
Eczema (atopic dermatitis) affects millions worldwide, yet many of its underlying mechanisms are still being uncovered. In this article, Professor Alan Irvine outlines what science understands about the condition’s causes — from the role of the skin barrier and immune pathways to the influence of the microbiome and environment — and explains how these insights are shaping innovative approaches to prevention and treatment.
Bridging the gap: Comparing topical drug absorption and activity in mouse and human skin models
Mouse models remain a cornerstone of dermatology research, but their differences from human skin — in follicle density, barrier function, and wound healing — can limit translation. This article explores the critical factors that shape absorption and pharmacological activity, and considers how human-based models can improve predictive power.
Why psoriasis research needs a human-relevant approach — and how ex vivo models can deliver
Explore how TenSkin™, Ten Bio’s ex vivo human skin model, is helping researchers study psoriasis with greater accuracy and human relevance — reducing reliance on animal testing and improving translational outcomes.
A season of global engagement in skin science and innovation
This spring, Ten Bio joined leading voices in dermatology at events in France, the US, and Australia—spotlighting TenSkin™ as a powerful, human-relevant alternative to animal testing. From photoprotection to microneedle delivery, the message was clear: innovation needs better models.
Ten Bio joins James Hutton Institute’s Dundee campus to advance dermatological research
Ten Bio has officially joined the James Hutton Institute’s Dundee campus, marking a new chapter in its mission to advance human-relevant dermatology research. The move supports Ten Bio’s continued growth and fosters collaboration with one of Scotland’s leading scientific communities.