Ten Bio News
Tissue integration of hyaluronic acid -containing dermal fillers: an optimized approach using tensioned ex-vivo human skin
Using the TenSkin™ ex-vivo model, this study highlights the importance of mechanical tension in assessing dermal filler integration. TenSkin™ provides a reliable platform for evaluating filler performance and guiding product development.
Precision solutions for your skin research challenges
At Ten Bio we enhance pre-clinical skin testing for our clients through the provision of our unique portfolio of explant skin platform TenSkin™. Our range includes large area models for novel drug delivery system evaluations, the adipose model for applications in subcutaneous injection delivery, and a wounded model for use in treatment & healing evaluations.
As we stride into 2024…
A very Happy and Prosperous New Year to all of Ten Bio’s clients current and future, suppliers, investors, and staff. We are all excited at the prospects of our business in 2024.
Happy Holidays 2023!
The Ten Bio team wishes you Happy Holidays and a Prosperous New Year! As our successful year comes to a close, we would like to thank our clients and business partners for their continued confidence, trust and engagement. We look forward to strengthening our collaborations in 2024 and are excited by the prospect of new partnerships and by the new science that will emerge in the coming year.
Bring me sunshine!
Exploring the effects of sun exposure using explant skin. Enjoyment of sunshine is a quintessential aspect of the human experience. Exposure provides a myriad of
Tension as a key factor in skin responses to pollution
This study explores how physiological tension affects skin responses to ozone pollution using the TenSkin™ model. Findings reveal tension modulates the expression of antimicrobial peptides and markers of oxidative stress and inflammation, highlighting its importance in skin health studies.
Advances and Opportunities in (Pre)Clinical Testing for Cosmetics and Personal Care
We are pleased to share this Global Perspectives Column in EURO COSMETICS Mag written by Deanna Utroske. Ten Bio emphasises scientific discipline and rigour in all of our
Scientific Conferences R Ten Bio
Since Ten Bio launched in the autumn of 2020 our attendance at conferences, symposia etc. has been the central plank to our market engagement strategy.
TenSkin™– its role in reducing animal testing in skin research.
TenSkinᵀᴹ – its role in reducing animal testing in skin research. Generate more predictive preclinical data without animal testing.
Mechanical tension influences the immunocompetency of ex vivo skin tissue
Human-relevant testing methods using donated skin tissue offer a promising alternative to animal models. Our ex vivo culture system restores physiological tension in skin, preserving structure, function, and immune cells like Langerhans cells, enabling immune activation studies for up to seven days.
A tensioned human skin explant model used for preliminary assessment of chemexfoliant-stimulated bioeffects
Our latest study, using the TenSkinᵀᴹ model, demonstrates how our ex vivo platform is delivering biologically relevant insights into the effects of chemexfoliation (chemical peel) treatments on human skin.
Ten Bio shortlisted for The Courier Business Awards
We are proud to be announced as finalist in The Courier Business Awards in the Innovation and Technology category.
The importance of using a diverse range of skin in aesthetic dermatology testing
The Ten Bio team explore why incorporating all Fitzpatrick types in aesthetic dermatology testing is not just a best practice – it is a scientific imperative.
Preliminary assessment of microneedle wound healing in a full-thickness ex vivo human skin model cultured at physiological tension
This study evaluated skin recovery using the TenSkin™ model after microneedle application (dissolvable and non-dissolving types). Histological and immunofluorescence analyses tracked wound healing, comparing results with laser ablation.
The effect of mechanical tension on bolus morphology and integration following intradermal injection in an ex vivo human skin model
Intradermal injection studies benefit from ex vivo human skin models, but traditional relaxed-state models lack physiological tension, impacting tissue integrity and fiber alignment. The TenSkin™ model addresses this, offering more accurate dermal responses and improved integration of hyaluronic acid-based fillers.
Ten Bio’s agile innovation in climate-smart skincare
At Ten Bio, we continually innovate to meet our client’s needs, helping them to overcome their R&D challenges and position themselves at the leading edge of their respective markets. Read about our agile innovation in climate-smart skincare in our latest article…