Ten Bio News
A tensioned human skin explant model used for preliminary assessment of chemexfoliant-stimulated bioeffects
Our latest study, using the TenSkinᵀᴹ model, demonstrates how our ex vivo platform is delivering biologically relevant insights into the effects of chemexfoliation (chemical peel) treatments on human skin.
Ten Bio shortlisted for The Courier Business Awards
We are proud to be announced as finalist in The Courier Business Awards in the Innovation and Technology category.
The importance of using a diverse range of skin in aesthetic dermatology testing
The Ten Bio team explore why incorporating all Fitzpatrick types in aesthetic dermatology testing is not just a best practice – it is a scientific imperative.
Preliminary assessment of microneedle wound healing in a full-thickness ex vivo human skin model cultured at physiological tension
This study evaluated skin recovery using the TenSkin™ model after microneedle application (dissolvable and non-dissolving types). Histological and immunofluorescence analyses tracked wound healing, comparing results with laser ablation.
The effect of mechanical tension on bolus morphology and integration following intradermal injection in an ex vivo human skin model
Intradermal injection studies benefit from ex vivo human skin models, but traditional relaxed-state models lack physiological tension, impacting tissue integrity and fiber alignment. The TenSkin™ model addresses this, offering more accurate dermal responses and improved integration of hyaluronic acid-based fillers.
Ten Bio’s agile innovation in climate-smart skincare
At Ten Bio, we continually innovate to meet our client’s needs, helping them to overcome their R&D challenges and position themselves at the leading edge of their respective markets. Read about our agile innovation in climate-smart skincare in our latest article…
The Sun Factor
Our patented TenSkin™ model can be used to evaluate the efficacy and tolerability of sunscreens, while also exploring the underlying biological processes that arise following exposure to the sun. In this article, the scientific team at Ten Bio explore the effects of sun exposure and the role of explant skin in the evaluation of sunscreen products and the investigation of the effects of over-exposure.
Ten Bio conferencing in 2024
Ken Fyvie shares plans for the 2024 conference season, read more to find out which events we will be attending.
Tissue integration of hyaluronic acid -containing dermal fillers: an optimized approach using tensioned ex-vivo human skin
Using the TenSkin™ ex-vivo model, this study highlights the importance of mechanical tension in assessing dermal filler integration. TenSkin™ provides a reliable platform for evaluating filler performance and guiding product development.
Precision solutions for your skin research challenges
At Ten Bio we enhance pre-clinical skin testing for our clients through the provision of our unique portfolio of explant skin platform TenSkin™. Our range includes large area models for novel drug delivery system evaluations, the adipose model for applications in subcutaneous injection delivery, and a wounded model for use in treatment & healing evaluations.
Setting the standard: How TenSkin is shaping regulatory change in skin testing
As regulators move away from animal testing, clear validation frameworks are needed to support alternatives. Explant models like TenSkin™ offer a human-relevant solution for preclinical skin research, improving predictability and reproducibility.
Pollution protection
Urban pollution drives demand for advanced skincare. Ten Bio’s TenSkin™ offers a next generation ex vivo model to test anti-pollution products, providing crucial insights that accelerate the development of scientifically validated, high-impact solutions.
Happy Holidays 2024
Spreading Holiday cheer – from the Ten Bio team to all of our clients, collaborators and partners – past, present and future! As the year winds down, we want to take a moment to express a heartfelt thank you for being a part of our journey through 2024.
The advantages of extended viability in TenSkin™ for dermatological research
Ten Bio’s TenSkin™ ex vivo human skin model offers two-week viability, enhancing the depth and reliability of skin studies, allowing for more detailed insights into skin health and treatment efficacy.
A tensioned human skin explant model used for preliminary assessment of chemexfoliant-stimulated bioeffects
Our latest study, using the TenSkinᵀᴹ model, demonstrates how our ex vivo platform is delivering biologically relevant insights into the effects of chemexfoliation (chemical peel) treatments on human skin.
Ten Bio shortlisted for The Courier Business Awards
We are proud to be announced as finalist in The Courier Business Awards in the Innovation and Technology category.