Microneedles
TenSkin™ a robust ex vivo platform for microneedle application
For successful evaluation of molecule delivery to skin during preclinical development, it is important to replicate the in vivo physiological and mechanical environment. Reproducible application of microneedle arrays depends heavily on both the tension present in skin tissue and the properties of the underlying substrate. The TenSkin™ platform restores skin’s mechanobiology to allow accurate recapitulation of the in vivo environment enabling generation of the most relevant preclinical data.
Full-thickness human skin complete with dermal and epidermal layers with appendages and minor skin cell populations, cultured at an optimum mechanical tension providing viability extending to beyond 2 weeks.