Immunocompetent model

Extended immune cell retention to provide accurate preclinical testing

Compared to traditional ex vivo models, the intact mechanobiology of TenSkin™  maintains the skin’s resident immune cells in a more normal state. When skin is removed from the body, an accelerated spontaneous migration of Langerhans cells (orange) occurs (10-20% of the cell population every 24 hours), limiting the practical window available for immune reaction studies. Culturing skin at physiological tension significantly reduces this rate of migration, allowing in-depth and extended assessments of immune response.